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Oxytocin and vasopressin analogs, and elucidating the role of EspJ

by Charlotte Sutherell

Rhiannon and Ed

Congratulations to Rhiannon on her recent paper!

Rhiannon's paper '' covers work completed during her PhD in the Tate Group. The report describes the synthesis and testing of new analogues of the nona-peptide oxytocin, which displayed favourable selectivity and potency as well as increased stability at higher temperatures. 

There was also a in April with scientists from 's research group at the  and researchers from the . The collaboration, including Tate Group member Kate Hadavizadeh, aimed to elucidate the role of ADP-ribosyltransferase effector EspJ and demonstrated the use of proteomics to study in vivo processes affected by a type III secretion system. 

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Reporter

Charlotte Sutherell

Department of Chemistry